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Lab Experiments

Introducing Dermatrix

Maximizing collagen production, naturally

Dermatrix Technology

At DREAMADERM, our pioneering technology is centered around the incredible capabilities of Dermatrix, a game-changing peptide that forms the foundation of our scientific approach. Dermatrix, a patented first-in-class topicl peptide, has been meticulously developed to promote collagen production and maintain optimal insulin levels within wounds during the healing process. It's not only highly effective but also cost-efficient and completely non-toxic.

Within the realm of skin models, Dermatrix shines by potentiating various insulin-induced processes. This includes boosting collagen mRNA transcription, amplifying the production of mature collagen protein, improving collagen secretion into the extracellular matrix, and energizing the migration of keratinocytes.


What sets Dermatrix apart is its versatility. It can be used independently, and it also seamlessly integrates with a wide range of products to cater to diverse needs. Our applications span multiple sectors, skincare ,cosmetics ,aesthetics veterinary care acute / chronic / post surgery wound care,with a particular focus on those linked to type-2 diabetes.

Rest assured, Dermatrix and related peptides are safeguarded by U.S. Patent No. 11,555,055, ensuring their innovative potential remains protected and available to you.

Explore the limitless possibilities of Dermatrix with us at DREAMADERM.

Our competition stop after stage two in the skin's healing process. Dermatrix continues forward to accelerate the skin's natural regenerative processes


Dermatrix Has

No risk of hypoglycemia

Non-toxic topical made of all-natural amino acids

Not subject to onerous regulation

At the Pharmacy

Solution with Dermatrix

DREAMADERM’s core technology promotes collagen production through an entirely new, science-based approach. 

Problems & Solution


Collagen production is absolutely essential for skin health / wound recovery and is also a principal goal of cosmetic treatments. Our technology exploits collagen production regulated by insulin.

Insulin is the key molecule responsible for directing cells to produce collagen.  However, insulin in the skin is being continuously destroyed by insulin-degrading enzyme (IDE), which is abundant in wound fluid.


Our patented, first-in-class peptide, Dermatrix, blocks insulin degradation,

thereby maximizing the skin's natural insulin level.

At the Pharmacy

Scientific Evidence

The development of Dermatrix has been supported by funding from the American Diabetes Association, National Institutes of Health, and UCI Beall Applied Innovation. UCI will be an equity partner with DREAMADERM, granting us access to UCI BAI business incubator, Innovation Corps training programs and office and wet lab space via University Lab Partners. Dermatrix represents the culmination of more than 22 years of effort by Dr. Leissring and other colleagues conducted at multiple prestigious institutions including:


Dermatrix™ potentiates several insulin-induced processes in skin models


increases transcription of collagen mrna


augments production of mature collagen protein


enhances secretion of collagen into the extracellular matrix



>22 years and >$6M in R&D

Dermatrix Applications

Increase insulin levels

IDE inhibitors have been shown to increase insulin levels and insulin action in vivo. For instance, a paper published by Dr. Leissring and other Harvard colleagues in the top journal, Nature, showed that this class of compounds exhibit multiple antidiabetic properties and—critically—increase the levels of insulin in the skin by blocking this enzyme.

All-natural amino acids

Dermatrix is a highly potent molecule composed of all-natural amino acids, making it relatively inexpensive to manufacture in a cGMP-compliant laboratory, costing less than $0.50 per treatment at scale.

Serve several verticals

Dermatrix and associated peptides can be utilized independently; however, they have the potential to be integrated with a vast array of products across multiple sectors. These sectors include skincare, cosmetics, aesthetics, veterinary services, and care for wounds—acute, chronic, and post-surgery. Moreover, they are recognized as a valid treatment option for chronic wounds, especially those associated with type-2 diabetes.

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